KPGXRSRHYNQIFN-UHFFFAOYSA-L 2-oxoglutarate(2-) Chemical compound C(=O)CCC(=O)C()=O KPGXRSRHYNQIFN-UHFFFAOYSA-L 0.000 abstract description 2.230000002407 ATP formation Effects 0.000 claims description 4.239000000126 substance Substances 0.000 claims description 5.239000004220 glutamic acid Substances 0.000 claims description 7.235000013922 glutamic acid Nutrition 0.000 claims description 7.229960002989 Glutamic Acid Drugs 0.000 claims description 7.102000004190 Enzymes Human genes 0.000 claims description 7.
229940009533 alpha-ketoglutaric acid Drugs 0.000 claims description 16.230000002438 mitochondrial Effects 0.000 claims description 21.JFCQEDHGNNZCLN-UHFFFAOYSA-N Glutaric acid Natural products OC(=O)CCCC(O)=O JFCQEDHGNNZCLN-UHFFFAOYSA-N 0.000 claims description 21.-1 glutaric acid compound Chemical class 0.000 claims description 36.KPGXRSRHYNQIFN-UHFFFAOYSA-N α-Ketoglutaric acid Chemical compound OC(=O)CCC(=O)C(O)=O KPGXRSRHYNQIFN-UHFFFAOYSA-N 0.000 claims description 38.ZKHQWZAMYRWXGA-KQYNXXCUSA-N Adenosine triphosphate Chemical compound ZKHQWZAMYRWXGA-KQYNXXCUSA-N 0.000 claims description 101.150000001875 compounds Chemical class 0.000 claims description 106.230000001965 increased Effects 0.000 claims abstract description 11.WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical class WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 claims abstract description 37.230000001629 suppression Effects 0.000 claims abstract description 55.201000010099 disease Diseases 0.000 title claims abstract description 45.
Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.) Filing date Publication date Priority claimed from US201461939092P external-priority Application filed by University of California filed Critical University of California Priority to CN202110294357.5A priority Critical patent/CN113082009A/en Publication of CN106163513A publication Critical patent/CN106163513A/en Status Pending legal-status Critical Current Links Original Assignee University of California Priority date (The priority date is an assumption and is not a legal conclusion.
Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.) 俊 邓刚 王何军 蒋美盛 Current Assignee (The listed assignees may be inaccurate.Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.) Pending Application number CN201580012347.0A Other languages Chinese ( zh)
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Google Patents For treating compositions and the method for old and feeble and age-related disease and symptomĭownload PDF Info Publication number CN106163513A CN106163513A CN201580012347.0A CN201580012347A CN106163513A CN 106163513 A CN106163513 A CN 106163513A CN 201580012347 A CN201580012347 A CN 201580012347A CN 106163513 A CN106163513 A CN 106163513A Authority CN China Prior art keywords experimenter plate compound cell atp Prior art date Legal status (The legal status is an assumption and is not a legal conclusion. Google Patents CN106163513A - For treating compositions and the method for old and feeble and age-related disease and symptom CN106163513A - For treating compositions and the method for old and feeble and age-related disease and symptom
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